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CMap Candidate Details

Structure:
CMap ID: C03265
Pert ID: BRD-A61221616
Compound Name: medroxyprogesterone-acetate
Targets:
MoA: progesterone receptor agonist
SMILES: C[C@H]1CC2C3CC[C@](OC(C)=O)(C(C)=O)[C@@]3(C)CCC2[C@@]2(C)CCC(=O)C=C12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123820 BRD-A61221616 A375 3.33 uM 24 h 0.0 0.0 0.0 -0.33 -1.13 0.97
123861 BRD-A61221616 A549 10 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.23
123879 BRD-A61221616 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123930 BRD-A61221616 HEK293 10 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.07
123955 BRD-A61221616 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124032 BRD-A61221616 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124083 BRD-A61221616 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124110 BRD-A61221616 MCF??7.00 3.33 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
124147 BRD-A61221616 MDAMB231 1.11 uM 24 h 0.23 0.94 0.06 -0.33 -1.1 0.87
124160 BRD-A61221616 PC3 1.11 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.57
124213 BRD-A61221616 THP1 10 uM 24 h 0.0 0.0 0.0 0.24 0.85 0.14
124266 BRD-A61221616 YAPC 3.33 uM 24 h 0.0 0.0 0.0 -0.21 -0.72 0.04
132246 BRD-A61221616 HT29 0.08 uM 24 h 0.28 1.15 0.32 0.36 1.29 1.49
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).