CMap Candidate Details
Structure:
| CMap ID: | C03271 |
| Pert ID: | BRD-K51324732 |
| Compound Name: | meglitinide |
| Targets: | CCR2 |
| MoA: | potassium channel blocker |
| SMILES: | COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)C(O)=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 124337 | BRD-K51324732 | HELA | 0.125 uM | 24 h | 0.38 | 1.58 | 1.51 | 0.0 | 0.0 | 0.0 |
| 124399 | BRD-K51324732 | JURKAT | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124444 | BRD-K51324732 | MCF10A | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.83 | 0.16 |
| 124508 | BRD-K51324732 | PC3 | 1.11 uM | 24 h | -0.27 | -1.13 | 0.4 | 0.22 | 0.76 | 0.05 |
| 132320 | BRD-K51324732 | A375 | 0.03 uM | 24 h | -0.24 | -1.01 | 0.16 | -0.24 | -0.81 | 0.13 |
| 132349 | BRD-K51324732 | A549 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132377 | BRD-K51324732 | HA1E | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.0 | 0.55 |
| 132408 | BRD-K51324732 | HEK293 | 0.01 uM | 24 h | -0.22 | -0.92 | 0.06 | 0.29 | 1.04 | 0.56 |
| 132454 | BRD-K51324732 | HT29 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.34 | 1.19 | 1.05 |
| 132516 | BRD-K51324732 | MCF??7.00 | 0.01 uM | 24 h | -0.21 | -0.85 | 0.01 | -0.28 | -0.93 | 0.34 |
| 132543 | BRD-K51324732 | MDAMB231 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132586 | BRD-K51324732 | THP1 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132635 | BRD-K51324732 | YAPC | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.84 | 0.18 |