CMap Candidate Details
Structure:
| CMap ID: | C03274 |
| Pert ID: | BRD-K14529030 |
| Compound Name: | meisoindigo |
| Targets: | STAT3 |
| MoA: | STAT inhibitor |
| SMILES: | CN1C(=O)\C(c2ccccc12)=C1\C(=O)Nc2ccccc12 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 122259 | BRD-K14529030 | A375 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122300 | BRD-K14529030 | HA1E | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122320 | BRD-K14529030 | HEK293 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.48 | -1.62 | 15.65 |
| 122393 | BRD-K14529030 | MCF??7.00 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.8 | 0.11 |
| 122482 | BRD-K14529030 | THP1 | 10 uM | 24 h | -0.24 | -1.01 | 0.17 | -0.22 | -0.73 | 0.05 |
| 130562 | BRD-K14529030 | A549 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130674 | BRD-K14529030 | HELA | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130714 | BRD-K14529030 | HT29 | 2.22 uM | 24 h | 0.22 | 0.93 | 0.05 | 0.0 | 0.0 | 0.0 |
| 130744 | BRD-K14529030 | MCF10A | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130788 | BRD-K14529030 | MDAMB231 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130816 | BRD-K14529030 | PC3 | 2.22 uM | 24 h | 0.31 | 1.31 | 0.75 | 0.0 | 0.0 | 0.0 |
| 130841 | BRD-K14529030 | YAPC | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |