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CMap Candidate Details

Structure:
CMap ID: C03281
Pert ID: BRD-A84174393
Compound Name: meloxicam
Targets: PTGS1|PTGS2
MoA: cyclooxygenase inhibitor
SMILES: CN1C(C(=O)Nc2ncc(C)s2)C(=O)c2ccccc2S1(=O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5168 BRD-A84174393 A375 10 uM 6 h -0.21 -0.89 0.04 0.33 1.17 0.97
5554 BRD-A84174393 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
21688 BRD-A84174393 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.89 0.26
37256 BRD-A84174393 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37559 BRD-A84174393 ASC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.62
37859 BRD-A84174393 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38400 BRD-A84174393 NPC 10 uM 24 h 0.0 0.0 0.0 0.2 0.72 0.02
38669 BRD-A84174393 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38892 BRD-A84174393 SKB 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.05
90933 BRD-A84174393 HUH7 10 uM 72 h 0.0 0.0 0.0 0.24 0.87 0.17
100357 BRD-A84174393 U2OS 10 uM 6 h 0.23 0.94 0.06 0.0 0.0 0.0
125636 BRD-A84174393 HEK293 0.37 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
125666 BRD-A84174393 HELA 0.125 uM 24 h -0.2 -0.82 0.0 0.0 0.0 0.0
125710 BRD-A84174393 HUVEC 0.125 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.8
125792 BRD-A84174393 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125863 BRD-A84174393 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125887 BRD-A84174393 THP1 0.125 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.4
125909 BRD-A84174393 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133684 BRD-A84174393 HA1E 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133783 BRD-A84174393 HT29 0.03 uM 24 h -0.19 -0.8 0.0 0.0 0.0 0.0
133816 BRD-A84174393 JURKAT 0.25 uM 24 h 0.21 0.89 0.02 0.25 0.87 0.17
133873 BRD-A84174393 MCF??7.00 0.74 uM 24 h 0.23 0.95 0.06 0.36 1.27 1.34
133899 BRD-A84174393 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).