CMap Candidate Details
Structure:
| CMap ID: | C03297 |
| Pert ID: | BRD-A83937277 |
| Compound Name: | mephenytoin |
| Targets: | SCN10A|SCN11A|SCN1A|SCN2A|SCN3A|SCN4A|SCN5A|SCN7A|SCN8A|SCN9A |
| MoA: | hydantoin antiepileptic |
| SMILES: | CCC1(NC(=O)N(C)C1=O)c1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 6703 | BRD-A83937277 | A375 | 10 uM | 24 h | -0.21 | -0.87 | 0.02 | 0.0 | 0.0 | 0.0 |
| 7122 | BRD-A83937277 | A549 | 10 uM | 6 h | 0.25 | 1.05 | 0.17 | 0.0 | 0.0 | 0.0 |
| 7275 | BRD-A83937277 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -0.99 | 0.51 |
| 7814 | BRD-A83937277 | HT29 | 10 uM | 24 h | -0.26 | -1.06 | 0.26 | -0.28 | -0.93 | 0.35 |
| 8629 | BRD-A83937277 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 52109 | BRD-A83937277 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 91081 | BRD-A83937277 | HUH7 | 15 uM | 72 h | 0.23 | 0.97 | 0.08 | 0.0 | 0.0 | 0.0 |
| 96397 | BRD-A83937277 | PC3 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |