CMap Candidate Details
Structure:
| CMap ID: | C03311 |
| Pert ID: | BRD-K09372874 |
| Compound Name: | merimepodib |
| Targets: | IMPDH1 |
| MoA: | inosine monophosphate dehydrogenase inhibitor |
| SMILES: | COc1cc(NC(=O)Nc2cccc(CNC(=O)O[C@H]3CCOC3)c2)ccc1-c1cnco1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121189 | BRD-K09372874 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.07 | 0.75 |
| 129245 | BRD-K09372874 | A375 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129254 | BRD-K09372874 | HA1E | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129275 | BRD-K09372874 | HELA | 2.22 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129300 | BRD-K09372874 | HT29 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129335 | BRD-K09372874 | MCF??7.00 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129352 | BRD-K09372874 | PC3 | 2.22 uM | 24 h | 0.25 | 1.03 | 0.13 | -0.34 | -1.16 | 1.1 |
| 129374 | BRD-K09372874 | YAPC | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |