CMap Candidate Details
Structure:
| CMap ID: | C03313 |
| Pert ID: | BRD-K28849549 |
| Compound Name: | mesalazine |
| Targets: | ALOX5|CHUK|IKBKB|MPO|PPARG|PTGS1|PTGS2 |
| MoA: | cyclooxygenase inhibitor; lipoxygenase inhibitor; prostanoid receptor antagonist |
| SMILES: | Nc1ccc(O)c(c1)C(O)=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24425 | BRD-K28849549 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24569 | BRD-K28849549 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.05 | 0.56 |
| 24888 | BRD-K28849549 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.12 | 0.95 |
| 25014 | BRD-K28849549 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25243 | BRD-K28849549 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25346 | BRD-K28849549 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 91352 | BRD-K28849549 | HUH7 | 20 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |