CMap Candidate Details
Structure:
| CMap ID: | C03316 |
| Pert ID: | BRD-K69688083 |
| Compound Name: | mestinon |
| Targets: | ACHE|BCHE |
| MoA: | cholinesterase inhibitor |
| SMILES: | CN(C)C(=O)Oc1ccc[n+](C)c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 50042 | BRD-K69688083 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50397 | BRD-K69688083 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121735 | BRD-K69688083 | HA1E | 10 uM | 24 h | 0.29 | 1.21 | 0.46 | -0.31 | -1.05 | 0.7 |
| 121764 | BRD-K69688083 | HELA | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121795 | BRD-K69688083 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121843 | BRD-K69688083 | PC3 | 10 uM | 24 h | -0.22 | -0.93 | 0.07 | 0.0 | 0.0 | 0.0 |
| 121869 | BRD-K69688083 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129757 | BRD-K69688083 | A375 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129829 | BRD-K69688083 | HEK293 | 2.22 uM | 24 h | -0.27 | -1.12 | 0.39 | -0.35 | -1.16 | 1.11 |
| 129917 | BRD-K69688083 | JURKAT | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.29 | 1.53 |
| 129956 | BRD-K69688083 | MCF10A | 0.74 uM | 24 h | 0.3 | 1.24 | 0.53 | 0.36 | 1.27 | 1.34 |
| 130000 | BRD-K69688083 | MCF??7.00 | 0.25 uM | 24 h | -0.28 | -1.15 | 0.43 | 0.0 | 0.0 | 0.0 |
| 130040 | BRD-K69688083 | MDAMB231 | 2.22 uM | 24 h | -0.24 | -1.0 | 0.15 | -0.28 | -0.96 | 0.43 |
| 130112 | BRD-K69688083 | THP1 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.8 | 0.11 |