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CMap Candidate Details

Structure:
CMap ID: C03328
Pert ID: BRD-A94709349
Compound Name: metaxalone
Targets:
MoA: muscle relaxant
SMILES: Cc1cc(C)cc(OCC2CNC(=O)O2)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4178 BRD-A94709349 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4531 BRD-A94709349 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4762 BRD-A94709349 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4866 BRD-A94709349 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
37112 BRD-A94709349 A375 10 uM 6 h 0.2 0.83 0.0 0.0 0.0 0.0
37261 BRD-A94709349 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37568 BRD-A94709349 ASC 10 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.16
38043 BRD-A94709349 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38252 BRD-A94709349 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38407 BRD-A94709349 NPC 10 uM 24 h 0.27 1.13 0.29 0.0 0.0 0.0
38674 BRD-A94709349 PHH 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 1.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).