CMap Candidate Details
Structure:
CMap ID: | C03343 |
Pert ID: | BRD-K54416256 |
Compound Name: | methimazole |
Targets: | TPO |
MoA: | antithyroid agent |
SMILES: | Cn1cc[nH]c1=S |
InchiKey: | |
Compound Aliases: |
Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
---|---|---|---|---|---|---|---|---|---|---|
51041 | BRD-K54416256 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.21 | 0.75 | 0.04 |
91226 | BRD-K54416256 | HUH7 | 30 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
124321 | BRD-K54416256 | HEK293 | 0.04 uM | 24 h | 0.31 | 1.28 | 0.63 | -0.22 | -0.73 | 0.04 |
124357 | BRD-K54416256 | HELA | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
124387 | BRD-K54416256 | HT29 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
124424 | BRD-K54416256 | JURKAT | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.02 | 0.61 |
132335 | BRD-K54416256 | A375 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
132362 | BRD-K54416256 | A549 | 0.08 uM | 24 h | 0.28 | 1.18 | 0.39 | 0.0 | 0.0 | 0.0 |
132392 | BRD-K54416256 | HA1E | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
132498 | BRD-K54416256 | MCF10A | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
132526 | BRD-K54416256 | MCF??7.00 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.86 | 0.22 |
132556 | BRD-K54416256 | MDAMB231 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.91 | 0.23 |
132573 | BRD-K54416256 | PC3 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.22 | 0.79 | 0.07 |
132612 | BRD-K54416256 | THP1 | 0.25 uM | 24 h | -0.31 | -1.29 | 0.79 | -0.31 | -1.06 | 0.72 |
132644 | BRD-K54416256 | YAPC | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.25 | 0.9 | 0.22 |