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CMap Candidate Details

Structure:
CMap ID: C03364
Pert ID: BRD-K16406336
Compound Name: methylene-blue
Targets: ACHE
MoA: guanylyl cyclase inhibitor; nitric oxide production inhibitor
SMILES: CN(C)c1ccc2nc3ccc(cc3[s+]c2c1)N(C)C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8920 BRD-K16406336 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9184 BRD-K16406336 A549 10 uM 6 h -0.37 -1.52 1.43 0.0 0.0 0.0
9373 BRD-K16406336 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9683 BRD-K16406336 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9911 BRD-K16406336 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10289 BRD-K16406336 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10472 BRD-K16406336 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10745 BRD-K16406336 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10953 BRD-K16406336 HT29 10 uM 24 h 0.22 0.91 0.03 0.0 0.0 0.0
11434 BRD-K16406336 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11999 BRD-K16406336 NCIH596 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.76 0.08
12278 BRD-K16406336 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12478 BRD-K16406336 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12996 BRD-K16406336 THP1 10 uM 6 h 0.0 0.0 0.0 0.21 0.75 0.04
13225 BRD-K16406336 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13454 BRD-K16406336 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96026 BRD-K16406336 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97654 BRD-K16406336 MCF??7.00 3.33 uM 6 h -0.3 -1.23 0.64 -0.3 -1.01 0.56
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).