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CMap Candidate Details

Structure:
CMap ID: C03370
Pert ID: BRD-K35240538
Compound Name: methylprednisolone
Targets: NR3C1
MoA: glucocorticoid receptor agonist
SMILES: C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
19019 BRD-K35240538 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
19448 BRD-K35240538 A549 10 uM 6 h -0.21 -0.89 0.03 0.0 0.0 0.0
19666 BRD-K35240538 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.4 -1.34 1.85
19992 BRD-K35240538 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.4 -1.34 1.85
20323 BRD-K35240538 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20647 BRD-K35240538 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
21236 BRD-K35240538 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
21738 BRD-K35240538 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91222 BRD-K35240538 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
95562 BRD-K35240538 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.22 0.8 0.08
95721 BRD-K35240538 U2OS 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.06 0.72
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).