CMap Candidate Details
Structure:
| CMap ID: | C03388 |
| Pert ID: | BRD-K52020312 |
| Compound Name: | metronidazole |
| Targets: | CYP2C9|CYP3A4 |
| MoA: | DNA inhibitor |
| SMILES: | Cc1ncc(n1CCO)[N+]([O-])=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24679 | BRD-K52020312 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25520 | BRD-K52020312 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 53032 | BRD-K52020312 | HEPG2 | 12 uM | 48 h | 0.27 | 1.11 | 0.25 | 0.27 | 0.96 | 0.34 |
| 53080 | BRD-K52020312 | MCF10A | 100 uM | 24 h | 0.28 | 1.15 | 0.34 | 0.0 | 0.0 | 0.0 |
| 91228 | BRD-K52020312 | HUH7 | 20 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 99633 | BRD-K52020312 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121558 | BRD-K52020312 | A375 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121597 | BRD-K52020312 | HA1E | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121635 | BRD-K52020312 | HELA | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121659 | BRD-K52020312 | HT29 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121678 | BRD-K52020312 | MCF??7.00 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.81 | 0.13 |
| 121702 | BRD-K52020312 | YAPC | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129688 | BRD-K52020312 | PC3 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |