CMap Candidate Details
Structure:
| CMap ID: | C00339 |
| Pert ID: | BRD-K52172416 |
| Compound Name: | anastrozole |
| Targets: | CYP19A1 |
| MoA: | aromatase inhibitor |
| SMILES: | CC(C)(C#N)c1cc(Cn2cncn2)cc(c1)C(C)(C)C#N |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 23080 | BRD-K52172416 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.39 | -1.32 | 1.71 |
| 24169 | BRD-K52172416 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 91146 | BRD-K52172416 | HUH7 | 12 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 118417 | BRD-K52172416 | A549 | 0.04 uM | 24 h | 0.28 | 1.18 | 0.39 | 0.0 | 0.0 | 0.0 |
| 118487 | BRD-K52172416 | HCC515 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121563 | BRD-K52172416 | A375 | 10 uM | 24 h | 0.31 | 1.31 | 0.76 | 0.0 | 0.0 | 0.0 |
| 121601 | BRD-K52172416 | HA1E | 10 uM | 24 h | -0.27 | -1.12 | 0.39 | 0.0 | 0.0 | 0.0 |
| 121639 | BRD-K52172416 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.2 | 1.21 |
| 121682 | BRD-K52172416 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129633 | BRD-K52172416 | HT29 | 0.25 uM | 24 h | -0.22 | -0.93 | 0.07 | 0.0 | 0.0 | 0.0 |
| 129692 | BRD-K52172416 | PC3 | 0.25 uM | 24 h | -0.33 | -1.38 | 1.09 | -0.25 | -0.84 | 0.18 |
| 129725 | BRD-K52172416 | YAPC | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |