CMap Candidate Details
Structure:
| CMap ID: | C03393 |
| Pert ID: | BRD-A64092382 |
| Compound Name: | mexiletine |
| Targets: | AHR|SCN4A|SCN5A |
| MoA: | sodium channel blocker |
| SMILES: | CC(N)COc1c(C)cccc1C |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 5272 | BRD-A64092382 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 5851 | BRD-A64092382 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 6142 | BRD-A64092382 | PC3 | 10 uM | 24 h | -0.23 | -0.94 | 0.08 | 0.0 | 0.0 | 0.0 |
| 6478 | BRD-A64092382 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 37091 | BRD-A64092382 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 37349 | BRD-A64092382 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 37530 | BRD-A64092382 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 38027 | BRD-A64092382 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 38159 | BRD-A64092382 | MCF??7.00 | 10 uM | 24 h | -0.19 | -0.8 | 0.0 | 0.0 | 0.0 | 0.0 |
| 38377 | BRD-A64092382 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50304 | BRD-A64092382 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.33 | 1.18 | 1.0 |
| 100263 | BRD-A64092382 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |