CMap Candidate Details
Structure:
| CMap ID: | C03396 |
| Pert ID: | BRD-K34328244 |
| Compound Name: | MF-101 |
| Targets: | CYP19A1|XDH |
| MoA: | estrogen receptor agonist |
| SMILES: | Oc1ccc(cc1)[C@@H]1CC(=O)c2ccc(O)cc2O1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 124939 | BRD-K34328244 | A375 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.06 | 0.59 |
| 124967 | BRD-K34328244 | A549 | 0.125 uM | 24 h | -0.34 | -1.42 | 1.43 | 0.0 | 0.0 | 0.0 |
| 124999 | BRD-K34328244 | HA1E | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 125028 | BRD-K34328244 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 125055 | BRD-K34328244 | HT29 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 125111 | BRD-K34328244 | MDAMB231 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.81 | 0.13 |
| 125132 | BRD-K34328244 | PC3 | 0.04 uM | 24 h | 0.18 | 0.76 | 0.0 | -0.28 | -0.94 | 0.37 |
| 125165 | BRD-K34328244 | THP1 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 133051 | BRD-K34328244 | HEK293 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.47 | -1.57 | 15.65 |
| 133158 | BRD-K34328244 | JURKAT | 0.08 uM | 24 h | 0.28 | 1.17 | 0.37 | 0.0 | 0.0 | 0.0 |
| 133198 | BRD-K34328244 | MCF10A | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 133227 | BRD-K34328244 | MCF??7.00 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 133317 | BRD-K34328244 | YAPC | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |