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CMap Candidate Details

Structure:
CMap ID: C03397
Pert ID: BRD-K60230970
Compound Name: MG-132
Targets: PSMB1
MoA: proteasome inhibitor
SMILES: CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1147 BRD-K60230970 A549 1.11 uM 24 h -0.19 -0.78 0.0 -0.26 -0.87 0.23
1183 BRD-K60230970 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3384 BRD-K60230970 HCC515 10 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.36
3975 BRD-K60230970 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41801 BRD-K60230970 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42409 BRD-K60230970 ASC 10 uM 24 h 0.2 0.84 0.0 -0.41 -1.39 2.02
42727 BRD-K60230970 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.23 1.28
43027 BRD-K60230970 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43895 BRD-K60230970 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44151 BRD-K60230970 SKB 10 uM 24 h 0.16 0.66 0.0 0.0 0.0 0.0
96261 BRD-K60230970 U2OS 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97516 BRD-K60230970 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.93
97617 BRD-K60230970 NKDBA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98762 BRD-K60230970 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99064 BRD-K60230970 NEU 10 uM 6 h 0.3 1.27 0.58 0.0 0.0 0.0
117430 BRD-K60230970 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120722 BRD-K60230970 JURKAT 20 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125660 BRD-K60230970 HEK293 20 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126092 BRD-K60230970 HUVEC 20 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128883 BRD-K60230970 YAPC 20 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130298 BRD-K60230970 HELA 20 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134267 BRD-K60230970 MDAMB231 20 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135223 BRD-K60230970 MCF10A 20 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).