CMap Candidate Details
Structure:
| CMap ID: | C00034 |
| Pert ID: | BRD-K22749967 |
| Compound Name: | ABT-239 |
| Targets: | HRH1|HRH2|HRH3 |
| MoA: | histamine receptor antagonist |
| SMILES: | C[C@@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C#N |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120864 | BRD-K22749967 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.39 | 1.36 | 1.76 |
| 120887 | BRD-K22749967 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120910 | BRD-K22749967 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120954 | BRD-K22749967 | HEK293 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121018 | BRD-K22749967 | HT29 | 10 uM | 24 h | -0.21 | -0.87 | 0.02 | 0.0 | 0.0 | 0.0 |
| 121042 | BRD-K22749967 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.2 | 0.71 | 0.02 |
| 121076 | BRD-K22749967 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.31 | 1.09 | 0.67 |
| 121110 | BRD-K22749967 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129163 | BRD-K22749967 | HELA | 2.22 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |