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CMap Candidate Details

Structure:
CMap ID: C03424
Pert ID: BRD-K06902185
Compound Name: minoxidil
Targets: ABCC9|KCNJ1|KCNJ10|KCNJ11|KCNJ8|PTGS1
MoA: KATP activator; Kir6 channel (KATP) activator; vasodilator
SMILES: Nc1cc(nc(N)[n+]1[O-])N1CCCCC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2983 BRD-K06902185 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3137 BRD-K06902185 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.69
3939 BRD-K06902185 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.32 1.71
44838 BRD-K06902185 ASC 10 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.62
45146 BRD-K06902185 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45952 BRD-K06902185 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46272 BRD-K06902185 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46587 BRD-K06902185 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98996 BRD-K06902185 NEU 10 uM 6 h -0.24 -1.02 0.18 0.0 0.0 0.0
122551 BRD-K06902185 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122581 BRD-K06902185 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122637 BRD-K06902185 HEK293 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122660 BRD-K06902185 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122683 BRD-K06902185 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122727 BRD-K06902185 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122797 BRD-K06902185 PC3 0.04 uM 24 h -0.27 -1.12 0.39 0.0 0.0 0.0
131049 BRD-K06902185 HUVEC 0.03 uM 24 h 0.0 0.0 0.0 -0.24 -0.79 0.11
131086 BRD-K06902185 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.63
131122 BRD-K06902185 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131188 BRD-K06902185 YAPC 2.22 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.19
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).