CMap Candidate Details
Structure:
| CMap ID: | C03428 |
| Pert ID: | BRD-K55420858 |
| Compound Name: | mirin |
| Targets: | MRE11A |
| MoA: | MRE11A exonuclease inhibitor |
| SMILES: | NC1=NC(=O)\C(S1)=C\c1ccc(O)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 33696 | BRD-K55420858 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.95 | 0.39 |
| 33813 | BRD-K55420858 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 34127 | BRD-K55420858 | ASC | 10 uM | 24 h | 0.22 | 0.9 | 0.02 | 0.0 | 0.0 | 0.0 |
| 34382 | BRD-K55420858 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 34644 | BRD-K55420858 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 34911 | BRD-K55420858 | HEPG2 | 10 uM | 6 h | 0.26 | 1.08 | 0.21 | -0.32 | -1.06 | 0.75 |
| 35163 | BRD-K55420858 | HT29 | 10 uM | 6 h | -0.26 | -1.1 | 0.35 | 0.0 | 0.0 | 0.0 |
| 35468 | BRD-K55420858 | MCF??7.00 | 10 uM | 6 h | 0.2 | 0.81 | 0.0 | -0.19 | -0.65 | 0.01 |
| 35800 | BRD-K55420858 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.27 | 0.97 | 0.34 |
| 35969 | BRD-K55420858 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 36286 | BRD-K55420858 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 36588 | BRD-K55420858 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 36837 | BRD-K55420858 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |