CMap Candidate Details
Structure:
| CMap ID: | C03437 |
| Pert ID: | BRD-A31204924 |
| Compound Name: | mitotane |
| Targets: | CYP11A1|CYP11B1|ESR1|FDX1 |
| MoA: | antineoplastic agent |
| SMILES: | ClC(Cl)C(c1ccc(Cl)cc1)c1ccccc1Cl |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 5261 | BRD-A31204924 | HA1E | 10 uM | 24 h | -0.24 | -1.01 | 0.15 | 0.0 | 0.0 | 0.0 |
| 5512 | BRD-A31204924 | HCC515 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.0 | 0.53 |
| 6460 | BRD-A31204924 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 37476 | BRD-A31204924 | ASC | 10 uM | 24 h | 0.19 | 0.78 | 0.0 | 0.0 | 0.0 | 0.0 |
| 37997 | BRD-A31204924 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 38142 | BRD-A31204924 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 38326 | BRD-A31204924 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 38624 | BRD-A31204924 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 118052 | BRD-A31204924 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 118096 | BRD-A31204924 | A549 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 118234 | BRD-A31204924 | HEPG2 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.22 | 1.25 |
| 118359 | BRD-A31204924 | PC3 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.4 | 1.4 | 2.18 |