CMap Candidate Details
Structure:
| CMap ID: | C03441 |
| Pert ID: | BRD-K21884483 |
| Compound Name: | mizolastine |
| Targets: | HRH1 |
| MoA: | histamine receptor antagonist |
| SMILES: | CN(C1CCN(CC1)c1nc2ccccc2n1Cc1ccc(F)cc1)c1nccc(=O)[nH]1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121372 | BRD-K21884483 | A375 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121443 | BRD-K21884483 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121525 | BRD-K21884483 | YAPC | 0.04 uM | 24 h | 0.3 | 1.24 | 0.53 | -0.29 | -0.99 | 0.5 |
| 129443 | BRD-K21884483 | HA1E | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129469 | BRD-K21884483 | HELA | 0.08 uM | 24 h | 0.27 | 1.11 | 0.26 | 0.0 | 0.0 | 0.0 |
| 129526 | BRD-K21884483 | MCF??7.00 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.92 | 0.33 |
| 129561 | BRD-K21884483 | PC3 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |