CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03446
Pert ID:	BRD-K38868394
Compound Name:	MK-0773
Targets:	AR
MoA:	androgen receptor modulator
SMILES:	CN1[C@@H]2CC[C@H]3[C@@H]4CC[C@H](C(=O)NCc5nc6cccnc6[nH]5)[C@@]4(C)CC[C@@H]3[C@@]2(C)C=C(F)C1=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
123228	BRD-K38868394	A375	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123417	BRD-K38868394	PC3	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123453	BRD-K38868394	THP1	3.33 uM	24 h	0.0	0.0	0.0	-0.31	-1.03	0.64
131543	BRD-K38868394	A549	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131578	BRD-K38868394	HA1E	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131620	BRD-K38868394	HEK293	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131654	BRD-K38868394	HELA	0.25 uM	24 h	0.0	0.0	0.0	-0.33	-1.11	0.88
131682	BRD-K38868394	HT29	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131714	BRD-K38868394	HUVEC	0.08 uM	24 h	0.0	0.0	0.0	-0.29	-0.99	0.51
131767	BRD-K38868394	JURKAT	0.01 uM	24 h	0.0	0.0	0.0	-0.35	-1.17	1.13
131817	BRD-K38868394	MCF10A	0.25 uM	24 h	-0.19	-0.8	0.0	0.0	0.0	0.0
131847	BRD-K38868394	MCF??7.00	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131884	BRD-K38868394	MDAMB231	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131949	BRD-K38868394	YAPC	0.03 uM	24 h	-0.23	-0.94	0.08	-0.2	-0.68	0.02

Summary