CMap Candidate Details
Structure:
| CMap ID: | C03461 |
| Pert ID: | BRD-K55512740 |
| Compound Name: | MK-8033 |
| Targets: | MET |
| MoA: | c-Met inhibitor |
| SMILES: | Cn1cc(cn1)-c1cnc2ccc3ccc(CS(=O)(=O)NCc4ccccn4)cc3c(=O)c2c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 96699 | BRD-K55512740 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.88 | 0.25 |
| 123582 | BRD-K55512740 | HEK293 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123622 | BRD-K55512740 | HELA | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.86 | 0.16 |
| 123698 | BRD-K55512740 | MCF10A | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131989 | BRD-K55512740 | A375 | 0.25 uM | 24 h | 0.25 | 1.05 | 0.16 | -0.26 | -0.87 | 0.23 |
| 132017 | BRD-K55512740 | HA1E | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.92 | 0.33 |
| 132061 | BRD-K55512740 | HT29 | 2.22 uM | 24 h | -0.2 | -0.83 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132090 | BRD-K55512740 | MCF??7.00 | 0.03 uM | 24 h | 0.34 | 1.41 | 1.03 | 0.0 | 0.0 | 0.0 |
| 132145 | BRD-K55512740 | YAPC | 0.03 uM | 24 h | 0.18 | 0.76 | 0.0 | -0.29 | -0.98 | 0.48 |