CMap Candidate Details
Structure:
| CMap ID: | C03462 |
| Pert ID: | BRD-K29656036 |
| Compound Name: | MK-8245 |
| Targets: | SCD |
| MoA: | stearoyl-CoA desaturase inhibitor |
| SMILES: | OC(=O)Cn1nnc(n1)-c1cc(no1)N1CCC(CC1)Oc1cc(F)ccc1Br |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 90610 | BRD-K29656036 | HCT116 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 90652 | BRD-K29656036 | MCF10A | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 98043 | BRD-K29656036 | MCF??7.00 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 98098 | BRD-K29656036 | P1A82 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.79 | 0.11 |
| 119957 | BRD-K29656036 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120002 | BRD-K29656036 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.36 | 1.27 | 1.34 |
| 120032 | BRD-K29656036 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120118 | BRD-K29656036 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120195 | BRD-K29656036 | PC3 | 1.11 uM | 24 h | -0.23 | -0.98 | 0.12 | -0.25 | -0.83 | 0.16 |
| 120220 | BRD-K29656036 | YAPC | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128838 | BRD-K29656036 | HELA | 2.22 uM | 3 h | -0.23 | -0.98 | 0.12 | 0.0 | 0.0 | 0.0 |