CMap Candidate Details
Structure:
| CMap ID: | C03467 |
| Pert ID: | BRD-A28422330 |
| Compound Name: | ML-141 |
| Targets: | CDC42 |
| MoA: | GTPase inhibitor |
| SMILES: | COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 13724 | BRD-A28422330 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 14191 | BRD-A28422330 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.98 | 0.47 |
| 14565 | BRD-A28422330 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.32 | 1.12 | 0.77 |
| 14937 | BRD-A28422330 | HT29 | 10 uM | 24 h | -0.18 | -0.76 | 0.0 | 0.0 | 0.0 | 0.0 |
| 15259 | BRD-A28422330 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 15563 | BRD-A28422330 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 16011 | BRD-A28422330 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |