CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03474
Pert ID:	BRD-K48188942
Compound Name:	ML-281
Targets:	STK33
MoA:	serine/threonine kinase inhibitor
SMILES:	CC(C)c1ccc(NC(=O)c2cccs2)c(c1)-c1nc2ccccc2[nH]c1=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
90726	BRD-K48188942	NOMO1	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
90752	BRD-K48188942	THP1	0.12 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
117683	BRD-K48188942	A375	3.33 uM	24 h	0.18	0.74	0.0	0.0	0.0	0.0
117730	BRD-K48188942	A549	0.125 uM	24 h	-0.28	-1.17	0.48	0.23	0.81	0.09
117777	BRD-K48188942	HA1E	0.04 uM	24 h	0.0	0.0	0.0	-0.28	-0.95	0.39
117827	BRD-K48188942	HCC515	10 uM	24 h	0.0	0.0	0.0	-0.31	-1.04	0.68
117877	BRD-K48188942	HEPG2	10 uM	24 h	0.3	1.24	0.53	-0.35	-1.17	1.11
117927	BRD-K48188942	HT29	10 uM	24 h	0.0	0.0	0.0	0.28	0.99	0.39
117974	BRD-K48188942	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
118021	BRD-K48188942	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary