CMap Candidate Details
Structure:
| CMap ID: | C00348 |
| Pert ID: | BRD-A75305484 |
| Compound Name: | anidulafungin |
| Targets: | |
| MoA: | fungal 1,3-beta-D-glucan synthase inhibitor |
| SMILES: | CCCCCOc1ccc(cc1)-c1ccc(cc1)-c1ccc(cc1)C(=O)NC1CC(O)C(O)NC(=O)C2C(O)C(C)CN2C(=O)C(NC(=O)C(NC(=O)C2CC(O)CN2C(=O)C(NC1=O)C(C)O)C(O)C(O)c1ccc(O)cc1)C(C)O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 127360 | BRD-A75305484 | A375 | 10 uM | 24 h | 0.2 | 0.83 | 0.0 | -0.29 | -0.97 | 0.46 |
| 127434 | BRD-A75305484 | HA1E | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.17 | 1.12 |
| 127471 | BRD-A75305484 | HELA | 10 uM | 24 h | 0.18 | 0.75 | 0.0 | 0.27 | 0.95 | 0.31 |
| 127487 | BRD-A75305484 | HT29 | 0.37 uM | 24 h | 0.19 | 0.78 | 0.0 | -0.3 | -1.01 | 0.57 |
| 127526 | BRD-A75305484 | JURKAT | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127560 | BRD-A75305484 | MCF10A | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127616 | BRD-A75305484 | PC3 | 1.11 uM | 24 h | -0.25 | -1.02 | 0.18 | 0.0 | 0.0 | 0.0 |
| 127652 | BRD-A75305484 | THP1 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.1 | 0.86 |
| 127696 | BRD-A75305484 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135348 | BRD-A75305484 | A549 | 0.01 uM | 24 h | -0.25 | -1.03 | 0.2 | 0.0 | 0.0 | 0.0 |
| 135477 | BRD-A75305484 | MCF??7.00 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |