CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03503
Pert ID:	BRD-K16485616
Compound Name:	mocetinostat
Targets:	HDAC1\|HDAC11\|HDAC2\|HDAC3
MoA:	HDAC inhibitor
SMILES:	Nc1ccccc1NC(=O)c1ccc(CNc2nccc(n2)-c2cccnc2)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
33687	BRD-K16485616	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
33892	BRD-K16485616	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
34839	BRD-K16485616	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
35104	BRD-K16485616	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
35300	BRD-K16485616	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
36213	BRD-K16485616	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
36508	BRD-K16485616	SKB	10 uM	24 h	0.16	0.65	0.0	0.0	0.0	0.0
36951	BRD-K16485616	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
93684	BRD-K16485616	ASC	3.33 uM	24 h	0.22	0.92	0.04	0.0	0.0	0.0
93716	BRD-K16485616	CD34	10 uM	24 h	0.24	1.01	0.11	0.0	0.0	0.0
93759	BRD-K16485616	HA1E	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
93794	BRD-K16485616	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
93843	BRD-K16485616	HEK293	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
93887	BRD-K16485616	HELA	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
93990	BRD-K16485616	HUVEC	10 uM	24 h	0.24	1.02	0.12	-0.32	-1.06	0.74
94027	BRD-K16485616	JURKAT	3.33 uM	24 h	0.21	0.89	0.02	0.0	0.0	0.0
94106	BRD-K16485616	NEU	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
94139	BRD-K16485616	NPC	0.12 uM	24 h	0.0	0.0	0.0	-0.26	-0.89	0.27
94193	BRD-K16485616	PC3	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
94239	BRD-K16485616	SHSY5Y	0.12 uM	24 h	0.0	0.0	0.0	-0.25	-0.84	0.18
94291	BRD-K16485616	SKL	3.33 uM	24 h	-0.25	-1.06	0.26	0.0	0.0	0.0
94338	BRD-K16485616	THP1	0.12 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
94381	BRD-K16485616	YAPC	10 uM	24 h	0.0	0.0	0.0	-0.29	-0.97	0.46
100146	BRD-K16485616	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary