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CMap Candidate Details

Structure:
CMap ID: C03509
Pert ID: BRD-K49372556
Compound Name: mofezolac
Targets: PTGS1
MoA: cyclooxygenase inhibitor
SMILES: COc1ccc(cc1)-c1noc(CC(O)=O)c1-c1ccc(OC)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25668 BRD-K49372556 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25945 BRD-K49372556 A549 10 uM 24 h -0.21 -0.86 0.01 -0.29 -0.96 0.44
26377 BRD-K49372556 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
26708 BRD-K49372556 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27011 BRD-K49372556 HCC515 10 uM 6 h 0.21 0.87 0.01 0.21 0.74 0.04
27320 BRD-K49372556 HT29 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.99 0.5
27562 BRD-K49372556 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
27951 BRD-K49372556 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28265 BRD-K49372556 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28652 BRD-K49372556 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
28896 BRD-K49372556 PHH 10 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.3
29495 BRD-K49372556 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.16 1.11
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).