CMap Candidate Details
Structure:
CMap ID: | C03515 |
Pert ID: | BRD-K60640630 |
Compound Name: | mometasone-furoate |
Targets: | NR3C1 |
MoA: | glucocorticoid receptor agonist |
SMILES: | C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)c1ccco1)C(=O)CCl |
InchiKey: | |
Compound Aliases: |
Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
---|---|---|---|---|---|---|---|---|---|---|
2912 | BRD-K60640630 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.17 | 1.11 |
3245 | BRD-K60640630 | HCC515 | 10 uM | 24 h | 0.22 | 0.93 | 0.05 | -0.26 | -0.89 | 0.26 |
3532 | BRD-K60640630 | PC3 | 10 uM | 24 h | 0.16 | 0.66 | 0.0 | 0.32 | 1.14 | 0.87 |
3844 | BRD-K60640630 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
41804 | BRD-K60640630 | A375 | 10 uM | 6 h | 0.21 | 0.88 | 0.02 | 0.0 | 0.0 | 0.0 |
42116 | BRD-K60640630 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.22 | 1.24 |
42413 | BRD-K60640630 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
42730 | BRD-K60640630 | HEPG2 | 10 uM | 6 h | -0.21 | -0.87 | 0.02 | -0.31 | -1.05 | 0.71 |
43030 | BRD-K60640630 | HT29 | 10 uM | 6 h | 0.21 | 0.88 | 0.02 | 0.0 | 0.0 | 0.0 |
43211 | BRD-K60640630 | MCF??7.00 | 10 uM | 24 h | -0.25 | -1.06 | 0.25 | -0.36 | -1.21 | 1.23 |
43594 | BRD-K60640630 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
43898 | BRD-K60640630 | PHH | 10 uM | 24 h | 0.22 | 0.9 | 0.02 | -0.22 | -0.75 | 0.06 |
44154 | BRD-K60640630 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.44 | -1.48 | 15.35 |