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CMap Candidate Details

Structure:
CMap ID: C03516
Pert ID: BRD-A78377521
Compound Name: monastrol
Targets: KIF11
MoA: kinesin inhibitor
SMILES: CCOC(=O)C1=C(C)NC(=S)NC1c1cccc(O)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2974 BRD-A78377521 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.8 0.12
3119 BRD-A78377521 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3703 BRD-A78377521 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39282 BRD-A78377521 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39594 BRD-A78377521 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39914 BRD-A78377521 HEPG2 10 uM 6 h -0.19 -0.81 0.0 0.0 0.0 0.0
40199 BRD-A78377521 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40437 BRD-A78377521 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.84
41018 BRD-A78377521 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41341 BRD-A78377521 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97039 BRD-A78377521 A375 10 uM 24 h -0.27 -1.14 0.42 0.0 0.0 0.0
97114 BRD-A78377521 PC3 3.33 uM 24 h 0.17 0.71 0.0 0.24 0.86 0.15
100331 BRD-A78377521 U2OS 15 uM 6 h 0.0 0.0 0.0 0.3 1.06 0.58
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).