CMap Candidate Details
Structure:
| CMap ID: | C00352 |
| Pert ID: | BRD-K91370081 |
| Compound Name: | anisomycin |
| Targets: | NHP2L1|RPL10L|RPL11|RPL13A|RPL15|RPL19|RPL23|RPL23A|RPL26L1|RPL3|RPL37|RPL8|RSL24D1 |
| MoA: | DNA synthesis inhibitor |
| SMILES: | COc1ccc(C[C@H]2NC[C@H](O)[C@H]2OC(C)=O)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 2942 | BRD-K91370081 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 3407 | BRD-K91370081 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.49 | -1.64 | 15.65 |
| 3651 | BRD-K91370081 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.48 | -1.62 | 15.65 |
| 39222 | BRD-K91370081 | A375 | 10 uM | 6 h | 0.3 | 1.24 | 0.53 | -0.47 | -1.59 | 15.65 |
| 39368 | BRD-K91370081 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.49 | -1.65 | 15.65 |
| 39823 | BRD-K91370081 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 40113 | BRD-K91370081 | HEPG2 | 10 uM | 6 h | 0.29 | 1.23 | 0.5 | -0.56 | -1.87 | 15.65 |
| 40374 | BRD-K91370081 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 40659 | BRD-K91370081 | MCF??7.00 | 10 uM | 6 h | 0.31 | 1.29 | 0.64 | -0.43 | -1.46 | 15.35 |
| 40921 | BRD-K91370081 | NEU | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.18 | 1.14 |
| 41587 | BRD-K91370081 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.45 | -1.52 | 15.35 |