Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C03524
Pert ID: BRD-K21548250
Compound Name: moracizine
Targets: SCN5A
MoA: sodium channel blocker
SMILES: CCOC(=O)Nc1ccc2Sc3ccccc3N(C(=O)CCN3CCOCC3)c2c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6980 BRD-K21548250 A549 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.01
7430 BRD-K21548250 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7637 BRD-K21548250 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7989 BRD-K21548250 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8806 BRD-K21548250 VCAP 10 uM 6 h 0.0 0.0 0.0 0.28 1.0 0.43
52137 BRD-K21548250 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99745 BRD-K21548250 U2OS 12 uM 6 h 0.25 1.03 0.14 0.34 1.2 1.11
121416 BRD-K21548250 HELA 0.04 uM 24 h 0.21 0.86 0.01 -0.26 -0.87 0.22
121483 BRD-K21548250 PC3 10 uM 24 h -0.18 -0.76 0.0 0.0 0.0 0.0
121523 BRD-K21548250 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129409 BRD-K21548250 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).