CMap Candidate Details
Structure:
CMap ID: | C03536 |
Pert ID: | BRD-K66615216 |
Compound Name: | moxifloxacin |
Targets: | TOP2A |
MoA: | bacterial DNA gyrase inhibitor |
SMILES: | COc1c(N2C[C@@H]3CCCN[C@@H]3C2)c(F)cc2c1n(cc(C(O)=O)c2=O)C1CC1 |
InchiKey: | |
Compound Aliases: |
Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
---|---|---|---|---|---|---|---|---|---|---|
1223 | BRD-K66615216 | A549 | 10 uM | 24 h | -0.26 | -1.1 | 0.34 | -0.26 | -0.87 | 0.24 |
1284 | BRD-K66615216 | MCF??7.00 | 10 uM | 48 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
1348 | BRD-K66615216 | U2OS | 10 uM | 48 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.86 | 0.22 |
34151 | BRD-K66615216 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
34661 | BRD-K66615216 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
34930 | BRD-K66615216 | HEPG2 | 10 uM | 6 h | -0.28 | -1.16 | 0.46 | 0.0 | 0.0 | 0.0 |
35600 | BRD-K66615216 | NEU | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.91 | 0.29 |
35821 | BRD-K66615216 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
36314 | BRD-K66615216 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.09 | 0.82 |
36612 | BRD-K66615216 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
36988 | BRD-K66615216 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
96332 | BRD-K66615216 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
96403 | BRD-K66615216 | PC3 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
125009 | BRD-K66615216 | HA1E | 10 uM | 24 h | 0.25 | 1.05 | 0.17 | -0.24 | -0.82 | 0.15 |
125062 | BRD-K66615216 | HT29 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.16 | 1.11 |
125184 | BRD-K66615216 | THP1 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.33 | 1.16 | 0.9 |
125223 | BRD-K66615216 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
133074 | BRD-K66615216 | HEK293 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.01 | 0.55 |
133101 | BRD-K66615216 | HELA | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.29 | 1.01 | 0.46 |
133180 | BRD-K66615216 | JURKAT | 0.01 uM | 24 h | -0.26 | -1.09 | 0.33 | 0.0 | 0.0 | 0.0 |
133209 | BRD-K66615216 | MCF10A | 2.22 uM | 24 h | 0.18 | 0.74 | 0.0 | 0.0 | 0.0 | 0.0 |
133272 | BRD-K66615216 | MDAMB231 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |