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CMap Candidate Details

Structure:
CMap ID: C03537
Pert ID: BRD-K81144366
Compound Name: moxisylyte
Targets:
MoA: adrenergic receptor antagonist
SMILES: CC(C)c1cc(OC(C)=O)c(C)cc1OCCN(C)C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
126386 BRD-K81144366 A549 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126453 BRD-K81144366 HEK293 0.04 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
126584 BRD-K81144366 PC3 10 uM 24 h 0.0 0.0 0.0 0.39 1.37 2.14
126613 BRD-K81144366 YAPC 3.33 uM 24 h 0.22 0.92 0.04 0.0 0.0 0.0
134357 BRD-K81144366 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134409 BRD-K81144366 HA1E 0.25 uM 24 h 0.23 0.97 0.08 0.33 1.16 0.9
134438 BRD-K81144366 HELA 0.25 uM 24 h 0.24 1.0 0.11 0.0 0.0 0.0
134473 BRD-K81144366 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134520 BRD-K81144366 HUVEC 0.25 uM 24 h 0.2 0.84 0.0 0.0 0.0 0.0
134545 BRD-K81144366 MCF10A 2.22 uM 24 h -0.29 -1.22 0.62 0.0 0.0 0.0
134575 BRD-K81144366 MCF??7.00 0.03 uM 24 h -0.26 -1.09 0.32 0.0 0.0 0.0
134608 BRD-K81144366 MDAMB231 0.01 uM 24 h 0.23 0.98 0.09 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).