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CMap Candidate Details

Structure:
CMap ID: C03550
Pert ID: BRD-K37618799
Compound Name: MRS-1220
Targets: ADORA2B|ADORA3
MoA: adenosine receptor antagonist
SMILES: Clc1ccc2nc(NC(=O)Cc3ccccc3)n3nc(nc3c2c1)-c1ccco1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4104 BRD-K37618799 HA1E 10 uM 24 h -0.18 -0.76 0.0 -0.35 -1.17 1.13
4425 BRD-K37618799 HCC515 10 uM 24 h -0.24 -1.02 0.18 -0.27 -0.9 0.28
4683 BRD-K37618799 PC3 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.14
4927 BRD-K37618799 VCAP 10 uM 24 h 0.0 0.0 0.0 0.21 0.73 0.03
39128 BRD-K37618799 A375 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.2
39322 BRD-K37618799 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39688 BRD-K37618799 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39998 BRD-K37618799 HEPG2 10 uM 6 h 0.31 1.3 0.72 -0.27 -0.91 0.29
40269 BRD-K37618799 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40468 BRD-K37618799 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40805 BRD-K37618799 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41108 BRD-K37618799 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41443 BRD-K37618799 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99902 BRD-K37618799 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
136432 BRD-K37618799 SHSY5Y 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).