CMap Candidate Details
Structure:
| CMap ID: | C03558 |
| Pert ID: | BRD-K19061412 |
| Compound Name: | mubritinib |
| Targets: | EGFR|ERBB2 |
| MoA: | protein tyrosine kinase inhibitor |
| SMILES: | FC(F)(F)c1ccc(\C=C\c2nc(COc3ccc(CCCCn4ccnn4)cc3)co2)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121357 | BRD-K19061412 | A375 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121494 | BRD-K19061412 | YAPC | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129424 | BRD-K19061412 | HA1E | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.08 | 0.65 |
| 129459 | BRD-K19061412 | HELA | 0.01 uM | 24 h | -0.28 | -1.16 | 0.46 | -0.2 | -0.67 | 0.02 |
| 129481 | BRD-K19061412 | HT29 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.1 | 0.86 |
| 129508 | BRD-K19061412 | MCF??7.00 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129545 | BRD-K19061412 | PC3 | 0.25 uM | 24 h | -0.22 | -0.9 | 0.04 | 0.0 | 0.0 | 0.0 |