CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03564
Pert ID:	BRD-K63750851
Compound Name:	mycophenolic-acid
Targets:	IMPDH1\|IMPDH2
MoA:	dehydrogenase inhibitor; inositol monophosphatase inhibitor
SMILES:	COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)CCC(O)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1265	BRD-K63750851	A549	10 uM	6 h	0.0	0.0	0.0	0.28	0.99	0.39
1308	BRD-K63750851	MCF??7.00	10 uM	6 h	0.25	1.06	0.19	0.0	0.0	0.0
1332	BRD-K63750851	U2OS	1.11 uM	24 h	0.23	0.95	0.06	0.0	0.0	0.0
53466	BRD-K63750851	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
53601	BRD-K63750851	HUH7	2.5 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
53683	BRD-K63750851	PHH	10 uM	24 h	0.0	0.0	0.0	-0.29	-0.96	0.43
128450	BRD-K63750851	HEK293	1.11 uM	24 h	0.0	0.0	0.0	-0.35	-1.18	1.15
128483	BRD-K63750851	HELA	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128510	BRD-K63750851	HT29	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128560	BRD-K63750851	JURKAT	3.33 uM	24 h	-0.18	-0.76	0.0	0.0	0.0	0.0
128599	BRD-K63750851	MCF10A	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128652	BRD-K63750851	MDAMB231	10 uM	24 h	0.0	0.0	0.0	0.24	0.84	0.13
128687	BRD-K63750851	PC3	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128732	BRD-K63750851	THP1	10 uM	24 h	-0.24	-1.01	0.16	-0.42	-1.41	2.02
136189	BRD-K63750851	A375	0.25 uM	24 h	0.27	1.12	0.26	-0.34	-1.13	0.99
136234	BRD-K63750851	HA1E	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
136387	BRD-K63750851	YAPC	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary