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CMap Candidate Details

Structure:
CMap ID: C03598
Pert ID: BRD-K18574842
Compound Name: nafcillin
Targets: CYP1A2|CYP3A4|SLC22A6
MoA: bacterial cell wall synthesis inhibitor
SMILES: CCOc1ccc2ccccc2c1C(=O)N[C@H]1[C@H]2SC(C)(C)[C@@H](N2C1=O)C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4077 BRD-K18574842 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4385 BRD-K18574842 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4662 BRD-K18574842 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4908 BRD-K18574842 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39098 BRD-K18574842 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39304 BRD-K18574842 A549 10 uM 24 h -0.2 -0.83 0.0 0.34 1.19 1.03
39640 BRD-K18574842 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39955 BRD-K18574842 HEPG2 10 uM 6 h 0.21 0.88 0.01 0.0 0.0 0.0
40236 BRD-K18574842 HT29 10 uM 6 h 0.0 0.0 0.0 -0.41 -1.37 2.02
40595 BRD-K18574842 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40763 BRD-K18574842 NEU 10 uM 24 h -0.2 -0.84 0.0 0.16 0.57 0.0
41064 BRD-K18574842 NPC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.34
41393 BRD-K18574842 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).