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CMap Candidate Details

Structure:
CMap ID: C03599
Pert ID: BRD-A67862938
Compound Name: naftidrofuryl
Targets:
MoA: adrenergic receptor antagonist
SMILES: CCN(CC)CCOC(=O)C(CC1CCCO1)Cc1cccc2ccccc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5275 BRD-A67862938 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
5541 BRD-A67862938 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5854 BRD-A67862938 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6481 BRD-A67862938 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37535 BRD-A67862938 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100289 BRD-A67862938 U2OS 10 uM 6 h -0.24 -1.02 0.18 0.0 0.0 0.0
126704 BRD-A67862938 HELA 0.125 uM 24 h 0.0 0.0 0.0 0.34 1.21 1.15
126757 BRD-A67862938 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126821 BRD-A67862938 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126864 BRD-A67862938 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126906 BRD-A67862938 PC3 0.125 uM 24 h 0.21 0.88 0.02 0.0 0.0 0.0
126924 BRD-A67862938 THP1 0.125 uM 24 h -0.3 -1.26 0.72 0.0 0.0 0.0
126979 BRD-A67862938 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134665 BRD-A67862938 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134689 BRD-A67862938 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134748 BRD-A67862938 HEK293 0.74 uM 24 h 0.26 1.08 0.21 -0.28 -0.95 0.41
134811 BRD-A67862938 HT29 0.25 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.28
134838 BRD-A67862938 HUVEC 2.22 uM 24 h 0.0 0.0 0.0 0.28 1.01 0.44
134915 BRD-A67862938 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.47
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).