CMap Candidate Details
Structure:
| CMap ID: | C03607 |
| Pert ID: | BRD-K67511046 |
| Compound Name: | naloxone |
| Targets: | CREB1|ESR1|OPRD1|OPRK1|OPRM1|TLR4 |
| MoA: | opioid receptor antagonist |
| SMILES: | Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 6796 | BRD-K67511046 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.22 | 0.8 | 0.08 |
| 7191 | BRD-K67511046 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 8022 | BRD-K67511046 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 8259 | BRD-K67511046 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 8404 | BRD-K67511046 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50222 | BRD-K67511046 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 51053 | BRD-K67511046 | VCAP | 10 uM | 24 h | 0.26 | 1.07 | 0.2 | -0.34 | -1.13 | 0.98 |
| 91302 | BRD-K67511046 | HUH7 | 10 uM | 72 h | -0.26 | -1.1 | 0.34 | -0.27 | -0.92 | 0.33 |
| 99369 | BRD-K67511046 | U2OS | 6.66 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |