CMap Candidate Details
Structure:
| CMap ID: | C03609 |
| Pert ID: | BRD-K88172511 |
| Compound Name: | naltrexone |
| Targets: | OPRD1|OPRK1|OPRM1|SIGMAR1 |
| MoA: | opioid receptor antagonist |
| SMILES: | Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 6809 | BRD-K88172511 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7034 | BRD-K88172511 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7489 | BRD-K88172511 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.28 | 1.0 | 0.42 |
| 20145 | BRD-K88172511 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 20483 | BRD-K88172511 | HEPG2 | 10 uM | 6 h | 0.26 | 1.08 | 0.21 | 0.0 | 0.0 | 0.0 |
| 20792 | BRD-K88172511 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 20975 | BRD-K88172511 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.32 | 1.13 | 0.84 |
| 21450 | BRD-K88172511 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 21811 | BRD-K88172511 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 91167 | BRD-K88172511 | HUH7 | 10 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |