CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03613
Pert ID:	BRD-K69195780
Compound Name:	NAN-190
Targets:	ADRA1A\|ADRA1B\|ADRA1D\|HTR1A\|HTR1F
MoA:	serotonin receptor agonist
SMILES:	COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
3046	BRD-K69195780	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
3252	BRD-K69195780	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
3535	BRD-K69195780	PC3	10 uM	24 h	0.23	0.96	0.07	0.0	0.0	0.0
3851	BRD-K69195780	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
44431	BRD-K69195780	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
44722	BRD-K69195780	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45300	BRD-K69195780	HEPG2	10 uM	6 h	0.22	0.93	0.05	0.22	0.78	0.07
45562	BRD-K69195780	HT29	10 uM	6 h	-0.29	-1.2	0.55	0.0	0.0	0.0
45711	BRD-K69195780	MCF??7.00	10 uM	24 h	-0.26	-1.1	0.35	0.0	0.0	0.0
46122	BRD-K69195780	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99397	BRD-K69195780	U2OS	10 uM	6 h	0.0	0.0	0.0	0.32	1.12	0.76

Summary