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CMap Candidate Details

Structure:
CMap ID: C03618
Pert ID: BRD-K77641333
Compound Name: naphazoline
Targets: ADRA1A|ADRA2A
MoA: adrenergic receptor agonist
SMILES: C(C1=NCCN1)c1cccc2ccccc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3260 BRD-K77641333 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.34
3860 BRD-K77641333 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45030 BRD-K77641333 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45320 BRD-K77641333 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46143 BRD-K77641333 NPC 10 uM 24 h 0.0 0.0 0.0 0.32 1.15 0.88
46459 BRD-K77641333 PHH 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.7
46783 BRD-K77641333 SKB 10 uM 24 h 0.29 1.21 0.46 -0.28 -0.95 0.41
91258 BRD-K77641333 HUH7 15 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
99497 BRD-K77641333 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
127365 BRD-K77641333 A375 3.33 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.63
127441 BRD-K77641333 HA1E 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127531 BRD-K77641333 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 -0.38 -1.27 1.43
127563 BRD-K77641333 MCF10A 1.11 uM 24 h -0.28 -1.18 0.5 0.22 0.79 0.07
127582 BRD-K77641333 MCF??7.00 1.11 uM 24 h 0.28 1.15 0.34 0.3 1.05 0.58
127620 BRD-K77641333 PC3 10 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.5
127704 BRD-K77641333 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135350 BRD-K77641333 A549 2.22 uM 24 h -0.24 -0.99 0.13 0.0 0.0 0.0
135378 BRD-K77641333 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135416 BRD-K77641333 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135505 BRD-K77641333 THP1 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).