CMap Candidate Details
Structure:
| CMap ID: | C03621 |
| Pert ID: | BRD-K59197931 |
| Compound Name: | naproxen |
| Targets: | PTGS1|PTGS2 |
| MoA: | cyclooxygenase inhibitor |
| SMILES: | COc1ccc2cc(ccc2c1)[C@H](C)C(O)=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 22804 | BRD-K59197931 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.08 | 0.81 |
| 23101 | BRD-K59197931 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24328 | BRD-K59197931 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 91156 | BRD-K59197931 | HUH7 | 15 uM | 72 h | -0.2 | -0.84 | 0.01 | 0.0 | 0.0 | 0.0 |
| 99702 | BRD-K59197931 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123570 | BRD-K59197931 | HEK293 | 0.125 uM | 24 h | -0.27 | -1.13 | 0.41 | -0.31 | -1.05 | 0.7 |
| 123646 | BRD-K59197931 | HT29 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.98 | 0.47 |
| 123687 | BRD-K59197931 | MCF10A | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131978 | BRD-K59197931 | A375 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.43 | -1.44 | 15.35 |
| 132010 | BRD-K59197931 | HA1E | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132035 | BRD-K59197931 | HELA | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132079 | BRD-K59197931 | MCF??7.00 | 0.01 uM | 24 h | 0.27 | 1.13 | 0.29 | 0.0 | 0.0 | 0.0 |
| 132110 | BRD-K59197931 | PC3 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132138 | BRD-K59197931 | YAPC | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |