CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03624
Pert ID:	BRD-K08832567
Compound Name:	naringenin
Targets:	CYP19A1\|CYP1B1\|ESR2\|GLO1\|HSD17B1
MoA:	aromatase inhibitor; TRPV antagonist
SMILES:	Oc1ccc(cc1)[C@@H]1CC(=O)c2c(O)cc(O)cc2O1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
95314	BRD-K08832567	A549	10 uM	48 h	0.28	1.16	0.35	0.23	0.82	0.1
95347	BRD-K08832567	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
95390	BRD-K08832567	U2OS	0.12 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121149	BRD-K08832567	A375	0.04 uM	24 h	0.0	0.0	0.0	0.31	1.11	0.72
121222	BRD-K08832567	HA1E	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121250	BRD-K08832567	HELA	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121311	BRD-K08832567	PC3	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129295	BRD-K08832567	HT29	0.25 uM	24 h	0.0	0.0	0.0	-0.31	-1.05	0.72
129369	BRD-K08832567	YAPC	2.22 uM	24 h	0.27	1.13	0.29	0.0	0.0	0.0

Summary