CMap Candidate Details
Structure:
| CMap ID: | C03628 |
| Pert ID: | BRD-K38287497 |
| Compound Name: | narlaprevir |
| Targets: | |
| MoA: | HCV inhibitor |
| SMILES: | CCCC[C@H](NC(=O)[C@@H]1[C@@H]2[C@H](CN1C(=O)[C@@H](NC(=O)NC1(CS(=O)(=O)C(C)(C)C)CCCCC1)C(C)(C)C)C2(C)C)C(=O)C(=O)NC1CC1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 123522 | BRD-K38287497 | A375 | 0.37 uM | 24 h | -0.21 | -0.88 | 0.03 | 0.0 | 0.0 | 0.0 |
| 123586 | BRD-K38287497 | HEK293 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.79 | 0.11 |
| 123624 | BRD-K38287497 | HELA | 10 uM | 24 h | 0.17 | 0.7 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123658 | BRD-K38287497 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123701 | BRD-K38287497 | MCF10A | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.11 | 0.9 |
| 123728 | BRD-K38287497 | MCF??7.00 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.1 | 0.86 |
| 123745 | BRD-K38287497 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123771 | BRD-K38287497 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132018 | BRD-K38287497 | HA1E | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.12 | 0.96 |