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CMap Candidate Details

Structure:
CMap ID: C03635
Pert ID: BRD-K61177364
Compound Name: NBI-27914
Targets: CRHR1
MoA: corticosteroid releasing factor receptor antagonist
SMILES: CCCN(CC1CC1)c1nc(C)nc(Nc2c(Cl)cc(Cl)cc2Cl)c1Cl
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4228 BRD-K61177364 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4450 BRD-K61177364 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4699 BRD-K61177364 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5098 BRD-K61177364 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39151 BRD-K61177364 A375 10 uM 6 h 0.3 1.24 0.51 -0.29 -0.98 0.48
39468 BRD-K61177364 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39724 BRD-K61177364 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40023 BRD-K61177364 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40296 BRD-K61177364 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40488 BRD-K61177364 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.54
40837 BRD-K61177364 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41143 BRD-K61177364 NPC 10 uM 24 h 0.0 0.0 0.0 -0.48 -1.6 15.65
41480 BRD-K61177364 SKB 10 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.15
99285 BRD-K61177364 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).