CMap Candidate Details
Structure:
| CMap ID: | C03641 |
| Pert ID: | BRD-K04956647 |
| Compound Name: | nebivolol |
| Targets: | ADRB1|ADRB2 |
| MoA: | adrenergic receptor antagonist |
| SMILES: | O[C@H](CNC[C@@H](O)[C@@H]1CCc2cc(F)ccc2O1)[C@H]1CCc2cc(F)ccc2O1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 122535 | BRD-K04956647 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.29 | 1.56 |
| 122566 | BRD-K04956647 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122594 | BRD-K04956647 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122652 | BRD-K04956647 | HELA | 10 uM | 24 h | 0.26 | 1.06 | 0.19 | 0.0 | 0.0 | 0.0 |
| 122671 | BRD-K04956647 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122701 | BRD-K04956647 | MCF10A | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122744 | BRD-K04956647 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122784 | BRD-K04956647 | PC3 | 10 uM | 24 h | -0.25 | -1.06 | 0.25 | -0.22 | -0.73 | 0.05 |
| 130926 | BRD-K04956647 | HEK293 | 0.74 uM | 24 h | 0.27 | 1.12 | 0.27 | -0.27 | -0.9 | 0.29 |
| 131023 | BRD-K04956647 | HUVEC | 0.74 uM | 24 h | -0.33 | -1.38 | 1.09 | 0.0 | 0.0 | 0.0 |
| 131108 | BRD-K04956647 | MDAMB231 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131172 | BRD-K04956647 | YAPC | 0.03 uM | 24 h | -0.18 | -0.76 | 0.0 | 0.0 | 0.0 | 0.0 |